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A Phase 2b clinical study evaluating oral pill XBB COVID-19 vaccine candidate against an approved mRNA vaccine comparator

Trial Profile

A Phase 2b clinical study evaluating oral pill XBB COVID-19 vaccine candidate against an approved mRNA vaccine comparator

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 18 Aug 2026

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At a glance

  • Drugs VXA CoV2-1 (Primary) ; COVID-19 vaccine
  • Indications COVID 2019 infections
  • Focus Therapeutic Use

Most Recent Events

  • 06 Aug 2026 According to a Vaxart media release, The Company expects to release topline efficacy and safety data from the complete study, comprising the 400 participants in the sentinel safety cohort and approximately 5,000 participants in the main cohort, in the first half of 2027.
  • 07 Jul 2026 Results published in the Media Release
  • 25 Jun 2026 According to a Vaxart media release, overall funding available for the trial is now approximately $345 million. The latest modification allows for the release of approximately $29 million for completion of the trial and exploratory analyses

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