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A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase 3 Trial of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Treatment-Naive Metastatic Pancreatic Ductal Adenocarcinoma

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Trial Profile

A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase 3 Trial of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Treatment-Naive Metastatic Pancreatic Ductal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 28 Jun 2025

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At a glance

  • Drugs Quemliclustat (Primary) ; Gemcitabine; Paclitaxel
  • Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
  • Focus Therapeutic Use
  • Acronyms PRISM-1
  • Sponsors Arcus Biosciences

Most Recent Events

  • 06 May 2025 According to an Arcus Biosciences media release, enrollment completion expected by the end of 2025.
  • 25 Feb 2025 According to an Arcus Biosciences media release, In February 2025, Arcus partner, Taiho, dosed their first patient in Japan for PRISM-1.
  • 28 Nov 2024 Status changed from not yet recruiting to recruiting.

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