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Study of ZWI-001 (uricase-polycarboxybetaine conjugate) to treat hyperuricemia in severe gout

Trial Profile

Study of ZWI-001 (uricase-polycarboxybetaine conjugate) to treat hyperuricemia in severe gout

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 01 Feb 2024

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At a glance

  • Drugs ZWI 001 (Primary)
  • Indications Gout
  • Focus Adverse reactions; Proof of concept

Most Recent Events

  • 01 Feb 2024 New trial record
  • 24 Jan 2024 According to a ZWI Therapeutics media release, ZWI-001 (uricase-polycarboxybetaine conjugate), has demonstrated preclinical proof of concept and is currently in development to treat hyperuricemia in severe gout. ZWI has gained meaningful guidance on CMC, non-clinical, and clinical plans from the FDA via an INTERACT meeting and is progressing toward filing an IND.

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