A Randomised, Double-Blind, Placebo-Controlled, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers
Latest Information Update: 19 Feb 2025
At a glance
- Drugs Lomonitinib (Primary) ; Rabeprazole
- Indications Acute myeloid leukaemia
- Focus First in man; Pharmacokinetics
- Sponsors Eilean Therapeutics
Most Recent Events
- 11 Nov 2024 According to a Lomond Therapeutics media release, data from this study has been accepted for a poster presentation at the upcoming American Society of Hematology (ASH) Annual Meeting, which will be held from December 7-10, 2024 in San Diego.
- 04 Apr 2024 According to a Eilean Therapeutics media release, company announce the clearance from the Human Research Ethics Committee in Australia for lomonitinib (ZE46-0134) allowing the company to proceed with a Phase I clinical trial in relapsed/refractory (R/R) AML.
- 01 Feb 2024 New trial record