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A Randomized, Double-Blind, Phase 3b Study to Evaluate the Short- and Long-Term Efficacy and Safety of Dual Targeted Therapy With Intravenous Vedolizumab and Oral Upadacitinib Compared With Intravenous Vedolizumab and Oral Placebo for Induction Followed by Intravenous Vedolizumab Monotherapy for Maintenance in the Treatment of Adults With Moderately to Severely Active Crohn's Disease

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Trial Profile

A Randomized, Double-Blind, Phase 3b Study to Evaluate the Short- and Long-Term Efficacy and Safety of Dual Targeted Therapy With Intravenous Vedolizumab and Oral Upadacitinib Compared With Intravenous Vedolizumab and Oral Placebo for Induction Followed by Intravenous Vedolizumab Monotherapy for Maintenance in the Treatment of Adults With Moderately to Severely Active Crohn's Disease

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 09 Jun 2025

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At a glance

  • Drugs Vedolizumab (Primary) ; Upadacitinib
  • Indications Crohn's disease
  • Focus Registrational; Therapeutic Use
  • Acronyms VICTRIVA
  • Sponsors Takeda

Most Recent Events

  • 17 Jan 2025 Status changed from not yet recruiting to recruiting.
  • 13 Aug 2024 Planned initiation date changed from 22 Jul 2024 to 8 Jan 2025.
  • 02 Feb 2024 New trial record

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