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A Multicenter, Randomized, Double-blind, Parallel-group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696/Amlodipine 200/2.5 mg, 200/5 mg and 200/10 mg Compared to LCZ696 200 mg Alone in Patients With Grade 1 and 2 Hypertension Not Adequately Controlled by LCZ696 200 mg Monotherapy

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Trial Profile

A Multicenter, Randomized, Double-blind, Parallel-group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696/Amlodipine 200/2.5 mg, 200/5 mg and 200/10 mg Compared to LCZ696 200 mg Alone in Patients With Grade 1 and 2 Hypertension Not Adequately Controlled by LCZ696 200 mg Monotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 23 Aug 2025

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At a glance

  • Drugs Sacubitril/valsartan (Primary) ; Amlodipine
  • Indications Essential hypertension
  • Focus Therapeutic Use
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 27 Mar 2025 Status changed from recruiting to active, no longer recruiting.
  • 27 Mar 2025 Planned End Date changed from 20 Jan 2026 to 25 Dec 2025.
  • 27 Mar 2025 Planned primary completion date changed from 15 Aug 2025 to 1 Jul 2025.

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