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A Multicenter, Randomized, Open-label, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced, Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

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Trial Profile

A Multicenter, Randomized, Open-label, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced, Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 29 Jul 2024

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At a glance

  • Drugs IBI 343 (Primary) ; Irinotecan; Paclitaxel
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms G-HOPE-001
  • Sponsors Innovent Biologics

    • Most Recent Events

    • 26 Jul 2024 Planned primary completion date changed from 30 Jun 2027 to 30 Dec 2026.
    • 24 Jul 2024 Planned End Date changed from 30 Jun 2027 to 31 Dec 2027.
    • 24 Jul 2024 Planned primary completion date changed from 30 May 2026 to 30 Jun 2027.

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