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A Phase 1A/1B PK/PD study assessing TX45 in healthy volunteers

Trial Profile

A Phase 1A/1B PK/PD study assessing TX45 in healthy volunteers

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 23 May 2025

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At a glance

  • Drugs TX-000045 (Primary)
  • Indications Cardiovascular disorders; Lung disorders
  • Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics; Proof of concept

Most Recent Events

  • 17 May 2025 According to a Tectonic Therapeutic media release, topline data from Part B of the Phase 1b study in another type of pulmonary hypertension patients,expected in the second half of 2025.
  • 17 May 2025 According to a Tectonic Therapeutic media release, complete results from Part A(n=19) of the Phase 1b clinical trial of TX45 in patients with Group 2 Pulmonary Hypertension in Heart Failure with preserved Ejection Fraction are being presented in a late-breaking, oral session at the European Society of Cardiology (ESC) Heart Failure 2025 Congress being held in Belgrade, Serbia.
  • 17 May 2025 Results presented in the Tectonic Therapeutic media release.

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