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A Phase 2 Trial of PD-L1 t-haNK, N-803 IL-15 Superagonist (Anktiva), and Cetuximab for Immunotherapy-treated Patients With Recurrent, Metastatic HNSCC (QUILT-505)

Trial Profile

A Phase 2 Trial of PD-L1 t-haNK, N-803 IL-15 Superagonist (Anktiva), and Cetuximab for Immunotherapy-treated Patients With Recurrent, Metastatic HNSCC (QUILT-505)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Jun 2025

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At a glance

  • Drugs Cetuximab (Primary) ; CST 101 (Primary) ; Nogapendekin alfa inbakicept (Primary)
  • Indications Carcinoma; Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms QUILT-505

Most Recent Events

  • 27 Feb 2025 According to an ImmunityBio media release, company to provide data from fully enrolled clinical trials ; in checkpoint relapsed NSCLC (QUILT-3.055, NSCLC Cohort) patients, as well as lymphopenia reversal across multiple tumor types (QUILT-3.055, all cohorts).
  • 18 Mar 2024 Status changed from not yet recruiting to recruiting.
  • 06 Feb 2024 New trial record

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