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A Randomized, Phase 2/3 Study to Evaluate the Optimal Dose, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

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Trial Profile

A Randomized, Phase 2/3 Study to Evaluate the Optimal Dose, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 02 Mar 2025

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At a glance

  • Drugs Budigalimab (Primary) ; Livmoniplimab (Primary) ; Carboplatin; Cisplatin; Pembrolizumab; Pemetrexed
  • Indications Anaplastic large cell lymphoma; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms LIVIGNO-4
  • Sponsors AbbVie
  • Most Recent Events

    • 28 Nov 2024 Planned End Date changed from 8 Oct 2031 to 1 Oct 2031.
    • 28 Nov 2024 Planned primary completion date changed from 8 Oct 2031 to 1 Oct 2031.
    • 17 Sep 2024 According to Trial design presented at the 49th European Society for Medical Oncology Congress, enrollment is ongoing in approx. 200 sites globally.

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