A Phase 1 Dose-Escalation Study in Adults With Severe IgE-Mediated Food Allergy, to Assess the Safety, Tolerability, and Pharmacodynamic Effects of Short-Term Linvoseltamab Treatment, A BCMAxCD3 Bispecific Antibody to Induce T-Cell Killing of IgE Producing Plasma Cells, on Top of Chronic Dupilumab Treatment, to Prevent the Formation of New IgE Producing Plasma Cells
Latest Information Update: 21 May 2025
At a glance
- Drugs Dupilumab (Primary) ; Linvoseltamab (Primary)
- Indications Food hypersensitivity
- Focus Adverse reactions
- Sponsors Regeneron Pharmaceuticals
Most Recent Events
- 14 May 2025 Planned End Date changed from 30 Oct 2025 to 28 Mar 2028.
- 14 May 2025 Planned primary completion date changed from 30 Oct 2025 to 28 Mar 2028.
- 11 Jul 2024 Planned End Date changed from 24 Apr 2026 to 30 Oct 2025.