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A Randomized, Double-Blind Study of The Efficacy and Safety of Trevogrumab, With or Without Garetosmab, in Addition to Semaglutide in Patients With Obesity

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Trial Profile

A Randomized, Double-Blind Study of The Efficacy and Safety of Trevogrumab, With or Without Garetosmab, in Addition to Semaglutide in Patients With Obesity

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Jan 2026

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At a glance

Most Recent Events

  • 17 Dec 2025 Planned End Date changed from 4 Nov 2026 to 30 Oct 2026.
  • 17 Dec 2025 Planned primary completion date changed from 13 May 2026 to 18 May 2026.
  • 17 Sep 2025 According to a Regeneron Pharmaceutical media release, After 26 weeks, patients enter into the weight-maintenance phase in which they receive either higher-dose trevogrumab monotherapy or placebo through the end of the trial (week 52).

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