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A First-in-Human, Phase 1 Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of a Single-Induction Dose of convertibleCARTM-T Cells Armed With MicAbodyTM Protein (ASP2802) Followed by Maintenance Booster Doses of the MicAbody Protein in Patients With CD20-Positive Relapsed or Refractory B-Cell Lymphomas

Trial Profile

A First-in-Human, Phase 1 Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of a Single-Induction Dose of convertibleCARTM-T Cells Armed With MicAbodyTM Protein (ASP2802) Followed by Maintenance Booster Doses of the MicAbody Protein in Patients With CD20-Positive Relapsed or Refractory B-Cell Lymphomas

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 08 Jan 2025

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At a glance

  • Drugs ASP 2802 (Primary)
  • Indications Anaplastic large cell lymphoma; B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Hodgkin's disease; Marginal zone B-cell lymphoma; Primary cutaneous anaplastic large cell lymphoma; T-cell lymphoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Astellas Pharma

Most Recent Events

  • 03 Jan 2025 According to ClinicalTrials.gov, The termination of the study was a business decision made by the sponsor
  • 03 Jan 2025 Status changed from recruiting to discontinued.
  • 28 Jun 2024 Planned End Date changed from 31 May 2031 to 31 Aug 2031.

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