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A Phase 1, Uncontrolled, Open-label, Non-randomized, Dose-escalation Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors, Followed by an Uncontrolled, Non-randomized Study and an Uncontrolled, Randomized Study in Patients With Esophageal Squamous Cell Carcinoma or Head and Neck Squamous Cell Carcinoma

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Trial Profile

A Phase 1, Uncontrolled, Open-label, Non-randomized, Dose-escalation Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors, Followed by an Uncontrolled, Non-randomized Study and an Uncontrolled, Randomized Study in Patients With Esophageal Squamous Cell Carcinoma or Head and Neck Squamous Cell Carcinoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Feb 2025

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At a glance

  • Drugs KK 2260 (Primary)
  • Indications Carcinoma; Head and neck cancer; Oesophageal cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man
  • Sponsors Kyowa Kirin

    • Most Recent Events

    • 05 Feb 2025 Planned number of patients changed from 139 to 169.
    • 05 Feb 2025 Planned End Date changed from 31 May 2029 to 30 Apr 2030.
    • 05 Feb 2025 Planned primary completion date changed from 30 Nov 2028 to 31 Oct 2029.

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