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A Phase I-II Study of Niraparib Plus Temozolomide "One Week on, One Week Off" in Patients With Recurrent Isocitrate Dehydrogenase (IDH) Wild Type Glioblastoma and IDH Mutant Gliomas.

Trial Profile

A Phase I-II Study of Niraparib Plus Temozolomide "One Week on, One Week Off" in Patients With Recurrent Isocitrate Dehydrogenase (IDH) Wild Type Glioblastoma and IDH Mutant Gliomas.

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Sep 2024

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At a glance

  • Drugs Niraparib (Primary) ; Temozolomide (Primary)
  • Indications Astrocytoma; Glioblastoma; Glioma; Oligodendroglioma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ONC-2022-001
  • Most Recent Events

    • 30 Aug 2024 Planned initiation date changed from 1 Mar 2024 to 1 Sep 2024.
    • 19 Feb 2024 New trial record

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