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A Master Protocol for the Multi-Cohort, Open-Label, Phase 1/2 Study of DCC-3084 as Monotherapy and in Combination With Other Antitumor Agents in Participants With Advanced Malignancies Driven by the MAPK Pathway

Trial Profile

A Master Protocol for the Multi-Cohort, Open-Label, Phase 1/2 Study of DCC-3084 as Monotherapy and in Combination With Other Antitumor Agents in Participants With Advanced Malignancies Driven by the MAPK Pathway

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 25 May 2025

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At a glance

  • Drugs DCC 3084 (Primary) ; Antineoplastics
  • Indications Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Deciphera Pharmaceuticals

Most Recent Events

  • 15 May 2024 Status changed from not yet recruiting to recruiting.
  • 23 Feb 2024 Status changed from planning to not yet recruiting.
  • 21 Feb 2024 According to a Deciphera Pharmaceuticals media release, Expects to initiate a Phase 1 study for DCC-3084, a potential best-in-class pan-RAF inhibitor, in the first half of 2024.

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