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A Phase III, Randomized, Double-blind Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Stage IIB, IIIA, or Select IIIB, PD-L1 Positive, Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy

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A Phase III, Randomized, Double-blind Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Stage IIB, IIIA, or Select IIIB, PD-L1 Positive, Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 01 Feb 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Tiragolumab (Primary)
  • Indications Carcinoma; Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions; Registrational
  • Acronyms SKYSCRAPER-15
  • Sponsors Roche

    • Most Recent Events

    • 04 Nov 2024 Trial focus shifted from efficacy to safety. New primary endpoint 'Percentage of Participants With Adverse Events (AEs)' added. All secondary endpoint cancelled. Study design changed from double blind to open-label.
    • 04 Nov 2024 Planned number of patients changed from 1150 to 56.
    • 04 Nov 2024 Planned End Date changed from 30 Jun 2039 to 31 Dec 2025.

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