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A Phase 2b, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy, Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine, MTBVAC, Against TB Disease in Adolescents and Adults Aged 14-45 Years, Living in a TB Endemic Region.

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Trial Profile

A Phase 2b, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy, Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine, MTBVAC, Against TB Disease in Adolescents and Adults Aged 14-45 Years, Living in a TB Endemic Region.

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Mar 2026

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At a glance

  • Drugs MTBVAC (Primary)
  • Indications Tuberculosis
  • Focus Therapeutic Use

Most Recent Events

  • 06 Mar 2026 Planned number of patients changed from 4300 to 5500.
  • 19 Sep 2025 Planned End Date changed from 1 Mar 2028 to 31 Mar 2028.
  • 19 Sep 2025 Planned primary completion date changed from 1 Mar 2028 to 31 Mar 2028.

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