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An Open-label, Single-arm, Multicenter, Prospective Study of Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

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Trial Profile

An Open-label, Single-arm, Multicenter, Prospective Study of Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

Status: Active, no longer recruiting
Phase of Trial: Phase IV

Latest Information Update: 14 Apr 2026

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At a glance

  • Drugs Lorlatinib (Primary)
  • Indications Brain metastases; Meningeal carcinomatosis; Non-small cell lung cancer
  • Focus Therapeutic Use

Most Recent Events

  • 09 Apr 2026 Planned primary completion date changed from 1 Jul 2025 to 30 Apr 2026.
  • 09 Apr 2026 Status changed from not yet recruiting to active, no longer recruiting.
  • 04 Mar 2024 New trial record

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