A Phase 2/3, Adaptive, Randomized, Open-label, Clinical Study to Evaluate Neoadjuvant and Adjuvant Intismeran Autogene (mRNA-4157) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care, and Pembrolizumab Monotherapy in Participants With Resectable Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (INTerpath-007)
Latest Information Update: 16 May 2025
At a glance
- Drugs Intismeran autogene (Primary) ; Pembrolizumab (Primary)
- Indications Skin cancer; Squamous cell cancer
- Focus Therapeutic Use
- Acronyms INTerpath-007
- Sponsors Merck Sharp & Dohme
Most Recent Events
- 29 Jan 2025 Planned End Date changed from 6 May 2033 to 5 Mar 2026.
- 29 Jan 2025 Planned primary completion date changed from 30 Apr 2029 to 5 Mar 2026.
- 29 Jan 2025 Status changed from recruiting to active, no longer recruiting.