Trial Profile

A pivotal Phase 2/3 ReSPECT-LM trial for treatment of breast cancer with leptomeningeal metastases

Status: Planning

Phase of Trial: Phase II/III

Latest Information Update: 24 Feb 2025

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At a glance

18 Feb 2025 According to the Plus Therapeutics Media Release, company announced that it has closed a private placement with aggregate initial upfront proceeds of approximately $3.7 million and received a $2.0 million advance payment from CPRIT as part of its existing $17.6 million grant award. This capital, along with expected grant allocations later in 2025, is expected to fully support the completion of two planned LM trials, strategically positioning the company for a pivotal trial in 2026.
14 Nov 2024 According to a Plus Therapeutics media release, company Obtained agreement from FDA to begin enrollment in the ReSPECT-LM multi-administration trial for patients with LM (IND 153715). The trial is expected to begin enrollment in early 2025 at seven U.S. trial sites
11 Mar 2024 New trial record

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