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Clinical Study to Evaluate the Safety and Efficacy of Single Dose Intravenous Infusion of CRISPR/Cas9-edited Autologous CD34 + Hematopoietic Stem/Progenitor Cells (BRL-101) in the Treatment of Severe Sickle Cell Disease

Trial Profile

Clinical Study to Evaluate the Safety and Efficacy of Single Dose Intravenous Infusion of CRISPR/Cas9-edited Autologous CD34 + Hematopoietic Stem/Progenitor Cells (BRL-101) in the Treatment of Severe Sickle Cell Disease

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 02 Aug 2024

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At a glance

  • Drugs BRL 101 (Primary)
  • Indications Sickle cell anaemia
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 31 Jul 2024 Planned number of patients changed from 1 to 3.
    • 31 Jul 2024 Status changed from not yet recruiting to recruiting.
    • 20 May 2024 Planned initiation date changed from 25 Apr 2024 to 25 Sep 2024.

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