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A phase I trial of IDE161 in combination with KEYTRUDA (pembrolizumab) in patients with microsatellite instability-, or MSI-, high and microsatellite stable, or MSS, endometrial cancer

Trial Profile

A phase I trial of IDE161 in combination with KEYTRUDA (pembrolizumab) in patients with microsatellite instability-, or MSI-, high and microsatellite stable, or MSS, endometrial cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Feb 2025

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At a glance

  • Drugs IDE 161 (Primary) ; Pembrolizumab (Primary)
  • Indications Endometrial cancer
  • Focus Adverse reactions
  • Sponsors IDEAYA Biosciences

Most Recent Events

  • 13 Feb 2025 According to an IDEAYA media release, first patient dosed in the Phase 1 trial evaluating IDE161 in combination with KEYTRUDA in patients with MSI-High and microsatellite stable (MSS) endometrial cancer. Targeting Phase 1 expansion in 2025.
  • 13 Feb 2025 According to an IDEAYA media release, the company is Targeting IDE161 expansion with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, and combo(s) with TOP1i ADCs in solid tumors in 2025
  • 10 Dec 2024 According to IDEAYA media release, company announced that it has dosed the first patient in this trial.

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