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Phase I/II Trial of Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

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Trial Profile

Phase I/II Trial of Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 May 2026

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At a glance

  • Drugs Pacritinib (Primary)
  • Indications Myelodysplastic syndromes; Myeloproliferative disorders
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 20 May 2026 Planned initiation date changed from 20 may 2026 to 25 May 2026.
  • 24 Apr 2026 Planned initiation date changed from 22 Apr 2026 to 29 Apr 2026.
  • 17 Apr 2026 Planned initiation date changed from 1 Apr 2026 to 22 Apr 2026.

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