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A prospective cohort single-centre study of antiviral plus anti-spike monoclonal antibody sotrovimab combination therapy vs. monotherapy for high-risk immunocompromised patients with mild-to-moderate SARS-CoV2 infection during the Omicron era

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Trial Profile

A prospective cohort single-centre study of antiviral plus anti-spike monoclonal antibody sotrovimab combination therapy vs. monotherapy for high-risk immunocompromised patients with mild-to-moderate SARS-CoV2 infection during the Omicron era

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Mar 2024

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At a glance

  • Drugs Nirmatrelvir+ritonavir (Primary) ; Remdesivir (Primary) ; Sotrovimab (Primary)
  • Indications COVID-19 pneumonia
  • Focus Therapeutic Use

    • Most Recent Events

    • 21 Mar 2024 New trial record
    • 01 Mar 2024 Results assessing efficacy and safety of antiviral plus anti-spike monoclonal antibody combination therapy vs. monotherapy for high-risk immunocompromised patients with mild-to-moderate SARS-CoV2 infection published in the International Journal of Antimicrobial Agents.

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