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A Phase III/IV Factorial Randomized Double-blind Trial to Compare the Addition of Dapagliflozin vs Placebo and Rosuvastatin/Ezetimibe Versus Pitavastatin in Patients With HIV on Integrase Strand Transfer Inhibitor-based Antiretrovirals With Elevated Metabolic Risk

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A Phase III/IV Factorial Randomized Double-blind Trial to Compare the Addition of Dapagliflozin vs Placebo and Rosuvastatin/Ezetimibe Versus Pitavastatin in Patients With HIV on Integrase Strand Transfer Inhibitor-based Antiretrovirals With Elevated Metabolic Risk

Status: Recruiting
Phase of Trial: Phase III/IV

Latest Information Update: 23 Apr 2025

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At a glance

  • Drugs Dapagliflozin (Primary) ; Ezetimibe/rosuvastatin (Primary) ; Pitavastatin (Primary)
  • Indications Cardiovascular disorders; Hyperlipoproteinaemia; Obesity
  • Focus Therapeutic Use
  • Acronyms OPTIMAR

    • Most Recent Events

    • 18 Apr 2025 Planned primary completion date changed from 1 Jul 2025 to 1 Jul 2026.
    • 18 Apr 2025 Status changed from not yet recruiting to recruiting.
    • 22 Mar 2024 New trial record

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