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CRIMSON: A Multicentre, Randomised, Sham-controlled (and Active Controlled in the USA), Double-masked, 72-week Trial to Study the Safety, Tolerability, Pharmacokinetics, and Efficacy of 3 Dosing Regimens of Intravitreal BI 764524 in Patients With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy

Trial Profile

CRIMSON: A Multicentre, Randomised, Sham-controlled (and Active Controlled in the USA), Double-masked, 72-week Trial to Study the Safety, Tolerability, Pharmacokinetics, and Efficacy of 3 Dosing Regimens of Intravitreal BI 764524 in Patients With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 11 Jul 2025

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At a glance

  • Drugs BI 764524 (Primary) ; Aflibercept
  • Indications Diabetic retinopathy
  • Focus Therapeutic Use
  • Acronyms CRIMSON

Most Recent Events

  • 21 May 2024 Planned number of patients changed from 175 to 178.
  • 21 May 2024 Status changed from not yet recruiting to recruiting.
  • 06 May 2024 According to Boehringer Ingelheim Media Release the study will start recruiting later this year

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