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A Phase 1 Double-blind, Randomized, Dose Finding Clinical Trial with an Open-label Run-in Part to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Flavivirus-naïve Adults Aged 18 to 49 Years

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Trial Profile

A Phase 1 Double-blind, Randomized, Dose Finding Clinical Trial with an Open-label Run-in Part to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Flavivirus-naïve Adults Aged 18 to 49 Years

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 12 Mar 2026

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At a glance

  • Drugs VLA-1601 (Primary) ; CpG 1018; Telratolimod
  • Indications Zika virus infection
  • Focus Adverse reactions
  • Sponsors Valneva

Most Recent Events

  • 09 Mar 2026 Status changed from active, no longer recruiting to completed.
  • 04 Nov 2025 Results published in the Media Release
  • 12 Aug 2025 According to a Valneva media release, Sentinel recruitment and vaccinations have been completed and results from the trial are expected this year.

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