Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

A phase I/II trial of arfolitixorin as a first-line treatment in combination with 5-FU-based chemotherapy in patients with metastatic colorectal cancer

Trial Profile

A phase I/II trial of arfolitixorin as a first-line treatment in combination with 5-FU-based chemotherapy in patients with metastatic colorectal cancer

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 May 2025

Price :
$35 *
Note:
  • Adis is an information provider.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
  • A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

  • Drugs Arfolitixorin (Primary) ; Fluorouracil (Primary)
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 28 Apr 2025 According to an Isofol Medical BA media release, first patient has been included in this trial.
  • 28 Apr 2025 According to an Isofol Medical media release, status changed from planning to recruiting. The study will be conducted in two stages, where phase Ib part will assess the benefit/risk profile of escalating dose. The second part of the trial compares, in line with FDA and EMA guidance, the highest dose from phase Ib with one of the lower doses, with efficacy parameters as primary endpoints.
  • 21 Mar 2025 According to an Isofol Medical BA media release, company announces that the regulatory authority in Germany, BfArM, has given their final approval for the initiation of this clinical trial. The study will initially be conducted in Germany, where patient recruitment will commence shortly. and Dr. Sebastian Stintzing is the investigator of this study.

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top