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A Phase II, Randomized, Open-label Study to Assess the Efficacy, Safety, and Pharmacokinetics (PK) of Maintenance Cabozantinib (XL184) Plus Best Supportive Care (BSC) Versus BSC in Children, Adolescents and Young Adults (AYA) With Unresectable Residual Osteosarcoma Either at Diagnosis or at First Relapse After Standard Treatment

Trial Profile

A Phase II, Randomized, Open-label Study to Assess the Efficacy, Safety, and Pharmacokinetics (PK) of Maintenance Cabozantinib (XL184) Plus Best Supportive Care (BSC) Versus BSC in Children, Adolescents and Young Adults (AYA) With Unresectable Residual Osteosarcoma Either at Diagnosis or at First Relapse After Standard Treatment

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 03 May 2025

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At a glance

  • Drugs Cabozantinib (Primary)
  • Indications Osteosarcoma
  • Focus Therapeutic Use
  • Acronyms CabOSTar
  • Sponsors Ipsen

Most Recent Events

  • 01 Nov 2024 Planned initiation date changed from 30 Sep 2024 to 31 Oct 2024.
  • 23 Sep 2024 Planned initiation date changed from 31 Jul 2024 to 30 Sep 2024.
  • 29 Jul 2024 Planned initiation date changed from 13 Jun 2024 to 31 Jul 2024.

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