A Phase 3, Randomized, Double-blind, Multicenter Study of MK-1084 in Combination With Pembrolizumab Compared With Pembrolizumab Plus Placebo as Firstline Treatment of Participants With KRAS G12C-Mutant, Locally Advanced or Metastatic NSCLC With PD-L1 TPS ≥50% (KANDLELIT-004)
Latest Information Update: 30 Apr 2026
At a glance
- Drugs Calderasib (Primary) ; Pembrolizumab (Primary)
- Indications Non-small cell lung cancer
- Focus Registrational; Therapeutic Use
- Acronyms KANDLELIT-004
- Sponsors Merck Sharp & Dohme
Most Recent Events
- 12 Mar 2026 Last checked against Clinical Trials Information System
- 17 Sep 2024 Trial design presented at the 49th European Society for Medical Oncology Congress
- 05 Apr 2024 New trial record