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A Phase 2, Open-label Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer

Trial Profile

A Phase 2, Open-label Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Aug 2025

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At a glance

  • Drugs Actinium 225 rosopatamab (Primary)
  • Indications Prostate cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors Convergent Therapeutics

Most Recent Events

  • 13 May 2025 Planned number of patients changed from 47 to 60.
  • 10 Feb 2025 According to Convergent Therapeutics media release, trial progress of the study will be presented at the American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium, which will take place February 13-15, 2025, in San Francisco, California.
  • 18 Nov 2024 According to a Convergent Therapeutics media release, company announced the receipt of the first shipments of non-carrier added (n.c.a.) Actinium 225 (Ac-225) from Cardinal Health.

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