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AKTive-001: a Phase 1/1b Multiple Cohort Trial of ALTA2618 in Patients with Advanced Solid Tumors with AKT1 E17K Mutation

Trial Profile

AKTive-001: a Phase 1/1b Multiple Cohort Trial of ALTA2618 in Patients with Advanced Solid Tumors with AKT1 E17K Mutation

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Apr 2025

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At a glance

  • Drugs ALTA 2618 (Primary)
  • Indications Breast cancer; Endometrial cancer; Gynaecological cancer; HER2 negative breast cancer; Male breast cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Acronyms AKTive-001
  • Sponsors Alterome Therapeutics
  • Most Recent Events

    • 13 Dec 2024 Study design were presented at the 47th Annual San Antonio Breast Cancer Symposium
    • 11 Dec 2024 According to the Florida Cancer Specialists & Research Institute Media Release, data from this study studies being presented this week at the San Antonio Breast Cancer Symposium.
    • 30 Oct 2024 According to an Alterome Therapeutics media release, company announced announced the dosing of the first patient in AKTive-001 and additional clinical sites across Europe, Asia and Australia will initiate enrollment over the next year.

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