Integrated Glofit and Ibrutinib as Novel Immune Therapy Evaluation in Treatment-Naive Mantle Cell Lymphoma (IGNITE MCL): A Phase Ib/II Study of Glofitamab Plus Ibrutinib With Obinutuzumab Pretreatment in MCL Patients ≥ 65 or Ages 18-64 With High-Risk Features
Latest Information Update: 10 Feb 2026
At a glance
- Drugs Glofitamab (Primary) ; Ibrutinib (Primary) ; Obinutuzumab (Primary)
- Indications Mantle-cell lymphoma
- Focus Adverse reactions; Therapeutic Use
Most Recent Events
- 30 Jan 2026 Status changed from not yet recruiting to recruiting.
- 20 Apr 2025 Planned End Date changed from 1 May 2029 to 1 Nov 2029.
- 20 Apr 2025 Planned primary completion date changed from 1 May 2027 to 1 Nov 2027.