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MATCH Treatment Subprotocol T: GDC-0449 (Vismodegib) in Patients With Tumors (Except Basal Cell Skin Carcinoma) With Smoothened (SMO) or Patched 1 (PTCH1) Mutations

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Trial Profile

MATCH Treatment Subprotocol T: GDC-0449 (Vismodegib) in Patients With Tumors (Except Basal Cell Skin Carcinoma) With Smoothened (SMO) or Patched 1 (PTCH1) Mutations

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Oct 2025

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At a glance

  • Drugs Vismodegib (Primary)
  • Indications Lymphoma; Multiple myeloma; Solid tumours
  • Focus Therapeutic Use
  • Acronyms MATCH - Subprotocol T

Most Recent Events

  • 04 Sep 2025 Planned End Date changed from 4 Nov 2025 to 31 Dec 2026.
  • 04 Sep 2025 Planned primary completion date changed from 4 Nov 2025 to 31 Dec 2026.
  • 29 Oct 2024 Planned End Date changed from 4 Nov 2024 to 4 Nov 2025.

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