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DISCERN: Dual Immune Strategy Versus Single Checkpoint Inhibition Efficacy Response in PDL-1 Negative Non-Small Cell Lung Cancer (NSCLC)

Trial Profile

DISCERN: Dual Immune Strategy Versus Single Checkpoint Inhibition Efficacy Response in PDL-1 Negative Non-Small Cell Lung Cancer (NSCLC)

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 29 Jan 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Pharmacodynamics; Therapeutic Use
  • Acronyms DISCERN
  • Most Recent Events

    • 27 Jan 2025 Planned End Date changed from 1 Jul 2027 to 1 Sep 2027.
    • 27 Jan 2025 Planned primary completion date changed from 27 Feb 2027 to 27 Apr 2027.
    • 27 Jan 2025 Planned initiation date changed from 31 Jan 2025 to 31 Mar 2025.

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