Trial Profile

A Phase 2 Trial of Maintenance Abemaciclib/Letrozole After Systemic Therapy in Patients With Advanced or Recurrent Estrogen Receptor Positive, Mismatch Repair Proficient, TP53 Wildtype Endometrial Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 16 Feb 2026

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At a glance

Drugs Abemaciclib (Primary) ; Letrozole (Primary) ; Pembrolizumab (Primary) ; Carboplatin; Paclitaxel
Indications Endometrial cancer
Focus Therapeutic Use
Acronyms ALPINE

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