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Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination with Defactinib (FAK Inhibitor) and Cetuximab in Patients with Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

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Trial Profile

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination with Defactinib (FAK Inhibitor) and Cetuximab in Patients with Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Mar 2025

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At a glance

Most Recent Events

  • 17 Mar 2025 Status changed from suspended to recruiting.
  • 07 Feb 2025 Status changed from not yet recruiting to suspended. Reason the study was stopped: PI Request.
  • 13 Dec 2024 Planned initiation date changed from 31 Oct 2024 to 1 Apr 2025.

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