Trial Profile

A Phase 1, Open-label, Dose Escalation and Dose Expansion, Multicenter Clinical Trial to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML)

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 06 Jan 2026

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At a glance

31 Dec 2025 Planned number of patients changed from 60 to 150.
23 Jul 2025 Treatment has been amended, number of arm has been changed from 8 to 11.
23 Jul 2025 Planned End Date changed from 1 Jan 2026 to 1 Dec 2027.

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