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A Phase I, Open-Label Study of CLN-978 in Patients With Treatment-Refractory Rheumatoid Arthritis (RA)

Trial Profile

A Phase I, Open-Label Study of CLN-978 in Patients With Treatment-Refractory Rheumatoid Arthritis (RA)

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Jun 2025

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At a glance

  • Drugs CLN 978 (Primary)
  • Indications Autoimmune disorders; Rheumatoid arthritis
  • Focus Therapeutic Use
  • Sponsors Cullinan Therapeutics

Most Recent Events

  • 29 May 2025 Status changed from planning to not yet recruiting.
  • 16 Apr 2025 According to Cullinan Therapeutics media release, the European Medicines Agency (EMA) approved the Clinical Trial Application (CTA) for CLN-978. Ricardo Grieshaber-Bouyer is global Principal Investigator for this trial.
  • 27 Feb 2025 According to Cullinan Therapeutics media release, the company expects to initiate this phase 1 study in rheumatoid arthritis (RA) in the second quarter of 2025.The company-sponsored trial will be designed and executed in collaboration with FAU Erlangen-Nuremberg in Germany and Universita Cattolica del Sacro Cuore, Rome in Italy.

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