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A Phase 2, Open-Label, Single Arm, Non-Controlled, Single-Stage Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Plexiform Neurofibroma and Neurofibromatosis Type 1

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Trial Profile

A Phase 2, Open-Label, Single Arm, Non-Controlled, Single-Stage Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Plexiform Neurofibroma and Neurofibromatosis Type 1

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 08 May 2025

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At a glance

  • Drugs HLX 1502 (Primary)
  • Indications Neurofibromatosis 1; Plexiform neurofibroma
  • Focus Therapeutic Use
  • Acronyms INSPIRE-NF1
  • Sponsors Healx

Most Recent Events

  • 04 May 2025 Planned End Date changed from 1 Aug 2027 to 1 Jan 2028.
  • 04 May 2025 Planned primary completion date changed from 1 Jul 2026 to 1 Dec 2026.
  • 24 Feb 2025 According to Healx media release, company announced the first patient has been dosed in INSPIRE-NF1, a Phase 2 trial evaluating the safety and efficacy of HLX-1502, an oral investigational therapy, in patients with neurofibromatosis type 1 (NF1).

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