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A Phase 2, Open-Label, Single Arm, Non-Controlled, Single-Stage Study to Evaluate the Safety and Effects of HLX-1502 in Patients with Plexiform Neurofibroma and Neurofibromatosis Type 1

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Trial Profile

A Phase 2, Open-Label, Single Arm, Non-Controlled, Single-Stage Study to Evaluate the Safety and Effects of HLX-1502 in Patients with Plexiform Neurofibroma and Neurofibromatosis Type 1

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Mar 2025

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At a glance

  • Drugs HLX 1502 (Primary)
  • Indications Neurofibromatosis 1; Plexiform neurofibroma
  • Focus Therapeutic Use
  • Acronyms INSPIRE-NF1
  • Sponsors Healx

    • Most Recent Events

    • 24 Feb 2025 According to Healx media release, company announced the first patient has been dosed in INSPIRE-NF1, a Phase 2 trial evaluating the safety and efficacy of HLX-1502, an oral investigational therapy, in patients with neurofibromatosis type 1 (NF1).
    • 13 Jan 2025 Planned End Date changed from 1 Nov 2027 to 1 Aug 2027.
    • 13 Jan 2025 Planned primary completion date changed from 1 May 2027 to 1 Jul 2026.

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