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A proof-of concept Phase 2b/3 trial of lonigutamab in thyroid eye disease (TED).

Trial Profile

A proof-of concept Phase 2b/3 trial of lonigutamab in thyroid eye disease (TED).

Status: Planning
Phase of Trial: Phase II/III

Latest Information Update: 23 Oct 2024

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At a glance

  • Drugs Lonigutamab (Primary)
  • Indications Graves ophthalmopathy
  • Focus Proof of concept; Registrational; Therapeutic Use
  • Most Recent Events

    • 16 Oct 2024 According to an ACELYRIN media release, experts and advocates of a scientific and patient advisory board will provide important strategic input and clinical expertise as ACELYRIN completes its Phase 2 trial of lonigutamab in TED and prepares to initiate Phase 3 program in first quarter of 2025.
    • 09 May 2024 According to an ACELYRIN media release, this Phase 2b/3 trial, designed to be the first of two registrational trials in TED, is planned to be initiated in the second half of 2024.
    • 22 Apr 2024 New trial record

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