Trial Profile

A Phase 1, Open-label, 3-Part, Drug-Drug Interaction Study to Evaluate the Effects of Inhibition and Induction of CYP3A4 on the Pharmacokinetics of Leramistat and to Assess the Effect of Leramistat on the Pharmacokinetics of Simvastatin in Healthy Adult Subjects

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 01 Aug 2024

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At a glance

Drugs Leramistat (Primary) ; Itraconazole; Phenytoin; Simvastatin
Indications Autoimmune disorders; Idiopathic pulmonary fibrosis; Rheumatoid arthritis
Focus Pharmacokinetics
Sponsors Istesso

29 Jul 2024 Planned number of patients changed from 36 to 48.
29 Jul 2024 Planned primary completion date changed from 31 May 2024 to 30 Sep 2024.
03 May 2024 Status changed from not yet recruiting to recruiting.

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