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A Phase 1, Open-Label, 2-Part, Single Dose, Crossover Study to Examine the Effect of Food and Cobicistat Administration on the Pharmacokinetics and Safety of Plixorafenib in Healthy Participants

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Trial Profile

A Phase 1, Open-Label, 2-Part, Single Dose, Crossover Study to Examine the Effect of Food and Cobicistat Administration on the Pharmacokinetics and Safety of Plixorafenib in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Mar 2025

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At a glance

  • Drugs Cobicistat (Primary) ; Plixorafenib (Primary)
  • Indications CNS cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Fore Biotherapeutics

Most Recent Events

  • 17 Mar 2025 Status changed from recruiting to completed.
  • 10 Dec 2024 Planned number of patients changed from 12 to 28.
  • 10 Dec 2024 Planned End Date changed from 25 Nov 2024 to 22 Dec 2024.

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