A Phase 3b/4 Randomized, Open-label, Efficacy Assessor-Blinded Study, to Evaluate the Efficacy and Safety of Upadacitinib for the Treatment of Adult Subjects With Moderate to Severe Atopic Dermatitis and Inadequate Response to Dupilumab (SWITCH-UP)
Latest Information Update: 30 Oct 2025
At a glance
- Drugs Dupilumab (Primary) ; Upadacitinib (Primary)
- Indications Atopic dermatitis
- Focus Registrational; Therapeutic Use
- Acronyms Switch-Up
- Sponsors AbbVie
Most Recent Events
- 29 Sep 2025 Planned number of patients changed from 300 to 200.
- 27 Jun 2025 Planned End Date changed from 1 Mar 2026 to 1 Mar 2027.
- 27 Jun 2025 Planned primary completion date changed from 1 Aug 2025 to 1 Aug 2026.