A Phase I/IIa Study to Evaluate the Efficacy of DB107-RRV (Formerly Toca511), Administered to Subjects At Time of Resection and Intravenously Thereafter, in Combination with DB107-FC (Formerly Toca FC) and Radiation Therapy or DB107-FC, Temozolomide (TMZ) and Radiation Therapy in Patients with Newly Diagnosed High Grade Glioma
Latest Information Update: 06 Mar 2025
At a glance
- Drugs Vocimagene amiretrorepvec-flucytosine gene therapy (Primary) ; Vocimagene amiretrorepvec-flucytosine gene therapy (Primary) ; Vocimagene amiretrorepvec-flucytosine gene therapy (Primary) ; Temozolomide
- Indications Glioblastoma; Glioma
- Focus Therapeutic Use
- Sponsors Denovo Biopharma
Most Recent Events
- 05 Mar 2025 According to Anova media release company announced enrollment of the first two patients in the highly anticipated study of DB107 for the treatment of brain tumors.
- 14 Feb 2025 Planned End Date changed from 31 Jan 2040 to 31 Jan 2042.
- 14 Feb 2025 Planned primary completion date changed from 31 Jan 2040 to 31 Jan 2028.