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A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice (TPC) in Participants With Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery

Trial Profile

A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice (TPC) in Participants With Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 27 Apr 2025

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At a glance

  • Drugs Pembrolizumab (Primary) ; Sacituzumab govitecan (Primary) ; Capecitabine
  • Indications Triple negative breast cancer
  • Focus Therapeutic Use
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 13 Dec 2024 Trial design presented at the 47th Annual San Antonio Breast Cancer Symposium
  • 17 Jun 2024 Status changed from not yet recruiting to recruiting.
  • 07 May 2024 New trial record

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