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An Open-Label Phase 2 Study to Evaluate the Efficacy, Safety and Tolerability of BMB-101 in Adults With Either Classic Absence Epilepsy (With or Without Eyelid Myoclonia (EEM; Jeavons Syndrome), OR Developmental Epileptic Encephalopathy (DEE).

Trial Profile

An Open-Label Phase 2 Study to Evaluate the Efficacy, Safety and Tolerability of BMB-101 in Adults With Either Classic Absence Epilepsy (With or Without Eyelid Myoclonia (EEM; Jeavons Syndrome), OR Developmental Epileptic Encephalopathy (DEE).

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 May 2025

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At a glance

  • Drugs BMB-101 (Primary)
  • Indications Epilepsy; Myoclonus
  • Focus Therapeutic Use
  • Acronyms BREAKTHROUGH
  • Sponsors Bright Minds Biosciences

Most Recent Events

  • 20 May 2025 According to Bright Minds Biosciences media release, Members of Bright Minds leadership team will review the therapeutic rationale for BMB-101 and discuss the BREAKTHROUGH study in its virtual R&D Day on Tuesday, May 20, 2025, from 10:00 am-11:30 am ET.
  • 28 Apr 2025 According to Bright Minds Biosciences media release, The company will host a Key Opinion Leaders presentation on 20th May 2025 ,which will include an overview of the BREAKTHROUGH study.
  • 12 Dec 2024 Status changed from not yet recruiting to recruiting.

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