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A Phase 2/3 Multicenter, Randomized, Double-Blind, Placebo-Controlled and Open-Label Extension Trial to Evaluate the Efficacy and Safety of Aficamten in a Pediatric Population With Symptomatic Obstructive Hypertrophic Cardiomyopathy

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Trial Profile

A Phase 2/3 Multicenter, Randomized, Double-Blind, Placebo-Controlled and Open-Label Extension Trial to Evaluate the Efficacy and Safety of Aficamten in a Pediatric Population With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 02 Dec 2025

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At a glance

  • Drugs Aficamten (Primary)
  • Indications Hypertrophic cardiomyopathy
  • Focus Registrational; Therapeutic Use
  • Acronyms CEDAR-HCM
  • Sponsors Cytokinetics

Most Recent Events

  • 06 Nov 2025 According to a Cytokinetics media release, We expect to continue patient enrollment of the adolescent cohort into 2026.
  • 07 Aug 2025 According to a Cytokinetics media release, expect to continue enrollment through 2025 to enable completion of enrollment in late 2026.
  • 07 Aug 2025 According to a Cytokinetics media release, company expect to complete patient enrollment of the adolescent cohort in 2H 2025.

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