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A Phase 2/3 Multicenter, Randomized, Double-Blind, Placebo-Controlled and Open-Label Extension Trial to Evaluate the Efficacy and Safety of Aficamten in a Pediatric Population With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Trial Profile

A Phase 2/3 Multicenter, Randomized, Double-Blind, Placebo-Controlled and Open-Label Extension Trial to Evaluate the Efficacy and Safety of Aficamten in a Pediatric Population With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 21 Aug 2026

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At a glance

  • Drugs Aficamten (Primary)
  • Indications Hypertrophic cardiomyopathy
  • Focus Registrational; Therapeutic Use
  • Acronyms CEDAR-HCM
  • Sponsors Cytokinetics

Most Recent Events

  • 18 Aug 2026 Planned number of patients changed from 62 to 65.
  • 18 Aug 2026 Status changed from recruiting to active, no longer recruiting.
  • 07 Aug 2026 According to a Cytokinetics media release, Recently completed patient enrollment in the adolescent cohort of CEDAR-HCM, a clinical trial of aficamten in a pediatric population with symptomatic oHCM.

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